The primary structure of rat ribosomal protein L37a

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Primary sequence of the human ribosomal protein L37a.

Mammalian ribosomes consist of 82 different proteins and several RNA molecules. Sequence analysis of ribosomal proteins is essential for structural and functional studies and for understanding the evolution of ribosomes (1). Using human lymphoblast RNA and ABC (ATP binding cassette) protein (2) specific primers, we amplified a fragment highly homologous to the rat ribosomal L37a cDNA (3, 4, 5) ...

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The covalent structure of the rat liver 60 S ribosomal subunit protein L39 was determined. Fourteen tryptic peptides were purified, and the sequence of each was established by a micromanual procedure; they accounted for all 50 residues of L39. The sequence of the NH2-terminal 32 residues of L39, obtained by automated Edman degradation of the intact protein, provided the alignment of the first s...

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The primary structure of rat ribosomal protein S3.

The amino acid sequence of rat ribosomal protein S3, which has been reported to form part of the binding site for initiation factors, was deduced from the sequence of nucleotides in a recombinant cDNA. Ribosomal protein S3 contains 243 amino acids and has a molecular weight of 26,643. Rat S3 and Xenopus laevis ribosomal protein S1 are homologous: There are 62 identities in 63 consecutive residu...

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The primary structure of rat liver ribosomal protein L37. Homology with yeast and bacterial ribosomal proteins.

The covalent structure of the rat liver 60 S ribosomal subunit protein L37 was determined. Twenty-four tryptic peptides were purified and the sequence of each was established; they accounted for all 111 residues of L37. The sequence of the first 30 residues of L37, obtained previously by automated Edman degradation of the intact protein, provided the alignment of the first 9 tryptic peptides. T...

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The primary structure of human ribosomal protein L12.

The ribosome serves as the site of protein synthesis in all cells. Biogenesis of the mammalian ribosome is a complex process involving the coordinated expression of four ribosomal RNA molecules and approximately 75 ribosomal proteins. In order to understand the mechanisms governing ribosome biosynthesis, it is necessary to elucidate the structure and organization of its components. A cDNA clone...

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ژورنال

عنوان ژورنال: European Journal of Biochemistry

سال: 1989

ISSN: 0014-2956,1432-1033

DOI: 10.1111/j.1432-1033.1989.tb14889.x